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J Clin Endocrinol Metab 100:40374047 Ihnatowicz P, Wtor P, Drywie M (2019) Supplementation in autoimmune thyroid Hashimotos disease

This can pose serious health risks to patients, as contaminated water can introduce infections or other complications when used in medical applications

Red flags that should stop the protocol Certain findings should trigger immediate discontinuation of one or both compounds: IGF-1 levels exceeding the age-appropriate upper normal limit on two consecutive tests Fasting glucose rising above 126 mg/dL or HbA1c above 6.5% (indicating new-onset diabetes) Liver enzymes (ALT or AST) exceeding three times the upper limit of normal Persistent severe nausea, vomiting, or abdominal pain suggesting gastroparesis or pancreatitis New or worsening carpal tunnel syndrome symptoms Peripheral edema that does not resolve with fluid management Any sign of an allergic or hypersensitivity reaction These red flags are not exhaustive

Sleep is extremely important, especially for mitochondrial health as well