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Knudsen L.B., Nielsen P.F., Huusfeldt P.O., Johansen N.L

doi: 10.3389/fimmu.2025.1712796 Received 25 September 2025 Revised 25 November 2025 Accepted 25 November 2025 Published 12 December 2025 Volume 16 - 2025 Edited by Remi J Creusot, Columbia University, United States Reviewed by Gustaf Christoffersson, Uppsala University, Sweden Maria Elisabetta Federica Palam, React4life S.p.A, Italy Updates Copyright 2025 Bisconti, Abreu, Nguyen, Stolfi, Corbezzolo, Gigli, Raineri, Cappellano, Polini, Gervaso, Chiocchetti and the FLAMIN-GO Consortium

Although these agents offer transformative therapeutic potential, their optimal use requires individualized care, careful patient selection, and ongoing safety surveillance