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Moreover, various transcription factors such as specificity protein 1 (SP1), activator protein 1 (AP-1), nuclear factor kappa-light-chain-enhancer of activated B cells (NF-B) and GATA1 were reported to play an important role in the regulation of GSTP1 expression ( Figure 1

It is composed of three essential amino acids: cysteine, glutamate, and glycine

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However, the confounding bias here is that the reason for prescribing alpha-GPC was to prevent or slow down cognitive decline or dementia.[ref] However, the possible increase in relative stroke risk is something to take into consideration with higher levels of alpha-GPC supplements in older adults