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In contrast to other AOMs, which either suppress appetite or inhibit fat absorption [23], GLP-1RAs reduce body weight in a number of ways, decreasing appetite and hunger, and increasing satiety, resulting in reduced energy intake [24,25,26]
In addition, a single cell undergoing NADPH-depleting ferroptosis may deplete the NADPH concentration of neighbor cells that are connected to the cytoplasm of this cell, which causes the synchronized necrosis of neighbor cells in a functional organ [90]
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