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Besides impairing neurons, 6-OHDA also induces PD-like motor and non-motor symptoms in rats (Ungerstedt, 1968

The MitoPark Mousean animal model of Parkinson's disease with impaired respiratory chain function in dopamine neurons

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(doi: 10.1097/HJH.0000000000001960) (PMID:30308595) Abstract Background: Combined congenic breeding and microarray gene expression profiling previously identified glutathione S-transferase m-type 1 (Gstm1) as a positional and functional candidate gene for blood pressure (BP) regulation in the stroke-prone spontaneously hypertensive (SHRSP) rat