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The receptor that spadin and PE-22-28 primarily bind to is TREK-1 (TIWK-related-potassium channel) which is mostly found in the brain and lung tissue, heart, smooth muscle, prostate, and specific areas of the pancreas
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In order to further solidify their findings, the researchers analyzed the expression of the cell proliferation marker and the proliferating cell nuclear antigen (PCNA) in tendon fibroblasts at the RNA expression level through the use of RT-PCR
It was suggested that hepcidin may be a vertebrate counterpart of cysteine-rich antimicrobial peptides produced in the fat body of insects due to the fact that the fat body of insects is the equivalent of the mammalian liver [156]
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