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Extracted data included title, trial name, the first author, publication year, country/region, dose, administration route, median follow-up time, sample size, age, sex, race, body mass index (BMI), smoke, blood pressure, glycated hemoglobin (HbA1c), T2DM duration, estimated glomerular filtration rate (eGFR), baseline CVD or CKD, and measures of effect assessed by the hazard ratio (HR) and its 95% confidence interval (CI) for each of the cardiovascular outcomes

Empirical evidence also suggests that while GLP-1 therapies may be useful in treating impulsive/addictive behaviours such as alcoholism and binge eating disorder, these therapies may have adverse effects, such as nausea, vomiting, and diarrhoea

Protein Priority Rule: On GLP-1 medication or during any diet, protein is the first macronutrient you plan, the first thing on your plate, and the last thing you cut

Research on GLP-1 receptor agonists shows that losing 10 to 15% of body weight can reduce the Apnea-Hypopnea Index (AHI) by 30 to 50%