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As we will discuss in the clinical evidence section, the story becomes more complicated when you move from animal models to human trials

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Abstract Tamoxifen is the gold standard drug for the treatment of breast cancer in pre and post-menopausal women

In all, mTORC1 signals serve as a central hub of amino acid sensing and a variety of metabolic regulatory pathways, including proteins, nucleotides, and lipids synthesis, as well as other anabolic or catabolic processes (Ben-Sahra and Manning, Amino Acid Metabolism and Epigenetics Epigenetic modification can regulate gene expression by activating or inhibiting gene transcription without changing the DNA sequence, ultimately affecting embryonic development, stem cell differentiation, senescence, and tumorigenesis (Brien et al., 2019)