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It simultaneously activates three crucial receptors involved in appetite regulation and glucose metabolism: GIP (Glucose-Dependent Insulinotropic Polypeptide) Receptor: GIP is an incretin hormone that stimulates insulin release in response to glucose and may also have effects on fat metabolism

Drugs Today 47 , 99107 (2011)

We also expect to initiate our first-in-human trial for SLIM-1 (Semaglutide ultra Long-acting IMplant in obesity) shortly, following regulatory approval obtained in late June

Healthcare Pathway Costs: Initial assessment and monitoring : Whether NHS or private, GLP-1 treatment requires baseline investigations (HbA1c, renal function, lipid profile) and ongoing monitoring every 36 months