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Mammalian mitochondrial CI is the largest respiratory enzyme, consisting of 45 subunits 15
This range translates to approximately 1.6 to 4.0 micrograms per kilogram of body weight when scaled from effective animal doses
It could be useful for those who cannot tolerate stimulants or as an add-on for partial benefit
[13] We posited that we could design a structured linker that aligned the two proteins in an optimal conformation, preserving the functionality of the original sensor while creating a more compact fusion with better expression and targetability
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