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Nat Rev Gastroenterol Hepatol 14(1):921 Phillip Dellinger R, Tomayko JF, Angus DC, Opal S, Cupo MA, McDermott S et al (2009) Efficacy and safety of a phospholipid emulsion (GR270773) in gram-negative severe sepsis: results of a phase II multicenter, randomized, placebo-controlled, dose-finding clinical trial