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The delivery of peptides to the brain is challenging due to their low metabolic stability, which decreases their duration of action, poor penetration of the blood-brain barrier (BBB), and their incompatibility with oral administration, typically resulting in the need for parenteral administration

The main outcome was mean reduction of melanin indices measured at six different sites

Research applications of the KLOW combination include investigation of multi-modal tissue repair mechanisms, studies of peptide synergism and interaction effects, examination of copper-peptide delivery systems, and exploration of combined anti-inflammatory and regenerative approaches

Erastin is an inhibitor of system xc in vitro