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Tirzepatide works as a dual GIP and GLP-1 receptor agonist, meaning it activates two separate incretin pathways simultaneously

Nutritional and lifestyle factors that may influence allodynia risk While no direct evidence links specific nutrients to semaglutide-associated allodynia, general neuropathic pain research identifies several nutritional and lifestyle factors that influence nerve health and pain sensitivity

Although a definitive connection has not been established, patients with risk factors for pancreatic disease should discuss the risks and benefits of Ozempic with their healthcare provider