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10.1016/j.pharep.2019.04.004 42 KanehisaM.SatoY.KawashimaM.FurumichiM.TanabeM

The activation of the OR10P1 receptor by binding famsin results in enhanced expression the gluconeogenic genes encoding glucose-6-phosphatase (G6PC) and the cytosolic version of phosphoenolpyruvate carboxykinase (PCK1), the lipolytic genes encoding carboxy ester lipase (CEL), pancreatic lipase (PNLIP), pancreatic lipase-related protein 2 (PNLIPRP2), and colipase (CLPS), the ketogenic gene encoding mitochondrial HMG-CoA synthase (HMGCS2), and the lipid oxidation gene encoding carnitine palmitoyltransferase 1 (CPT1A)

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