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Genes Tested 5-HT2A 9p21 ABCG2 (Q141K) ACAT1-02 ACE1 G2350A ACE2 A8790G ACSL1 ACTN3 ADD1 ADIPOQ ADRB2 AGTR1 ALDH2 ANKK1 APB1 APOA2 APOE ARMS2 ATM D1853N BCMO1 A379V BCMO1 R267S BDNF CAT C-262T CBS CBS 191150T CBS A13637G CFH COL1A1 COMT COQ2 CTH CYP1A1 CYP1A2 CYP1B1*6 L432V CYP2C19*17 CYP2C9*3 A1075C CYP2D6 T100C CYP2E1 CYP2R1 CYP3A4*1B DAO C2029G DHFR A20965G DHFR C19483A DI01 DI02 ESR2 F5 FAAH FADS1 FADS2 FTO FUT2 GAD1 GATA3 GPX1 GSTM1 GSTP1 C341T GSTP1 I105V HFE-C282Y HLA DQ2.5 HLA-DQ8 HNMT HNMT C314T IL6 LCT LPA LZTFL1 MAO-A MDM2 MLH1 MTHFD1 G1958A MTHFR 1298 MTHFR 677 MTNR1B MTR A2756G MTRR A66G NAT2 NBPF3 NOS1 NOS2 PEMT PON1 PPAR-alpha PPARGC1A PPCDC SELENBP1 SHBG SIRT1 SLC17A7 SLC23A1 SOD2 SOD3 TCF7L2 TCN2 C766G TFR2 TMPRSS2 TP53 VKORC1*2 XRCC3 VeriTek Process AUTOMATED SYSTEMS SUPERIOR ASSAY PREPARATION DUPLICATE TESTING EXTERNAL ACCOUNTABILITY Need Assistance With Specimen Collection

79 Patients diagnosed with ABCB4 mutations as adults were observed to have less severe phenotypes, such as ICP and LPAC

Liver detoxification

NADPH oxidase 2 (NOX2), a biomarker of ferroptosis, markedly increased post-TBI in the ipsilateral cortex, especially in the microglia and macrophages at 4 and 7 days [137, 142]