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The visual increase in Hoechst fluorescence intensity following M+D and M+D+V treatments can be explained by accumulation of the dye due to highly condensed and fragmented DNA ( Supplementary Figure S2 )

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Schedule Your Assessment MOTS-c: Helping Tired Cells Use Fuel Better If youve ever felt like: Carbs hit you harder than they used to You gain quickly from small off-plan choices You crash when you push through workouts or long days Youre feeling something we call metabolic inflexibility your cells struggle to shift gears between different fuel sources

In summary, we identified ER stress as the main adaptive stress response caused by AQ-QI and DEAQ-QI and evaluated the protective role of GSTP1 using a transfected HepG2 cell model