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If you're extremely constipated, it's best to talk with your doctor about using a laxative (such as an osmotic laxative or suppository) to remove the trapped stool

When manufacturers decide on an expiration date, they consider how long semaglutide will stay stable and effective in normal storage situations

Tiniakos, Gyongyi Szabo, Jun Yu, Chantal Desdouets, Frank Tacke, Fiona Oakley, Mathias Heikenwalder Journal of Hepatology .2026

In a recent review published in the Journal of Clinical and Translational Hepatology , researchers explore the therapeutic potential and clinical insights of glucagon-like peptide-1 receptor agonists (GLP-1RAs) in the management of metabolic dysfunction-associated steatotic liver disease (MASLD)