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Last reviewed: May 29, 2026 Last updated: May 29, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

You find yourself needing ibuprofen daily or multiple times a week

Animal studies in diet-induced obese rats show tesofensine treatment produces improvements in metabolic status including increased insulin sensitivity, reductions in plasma lipid levels, and enhanced glucose homeostasis

In particular, adipose tissue, or fat cells, produce hormones known as adipokines, which regulate metabolism and appetite