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[] Despite the benefits of using DFO to treat a variety of human diseases, essentially iron overload-associated pathologies, administration of this siderophore can result in certain adverse effects, which encompass failure of human development, bone dysplasia, retinal pigment epithelium modification, visual impairment, decreased night vision as well as impairments to the cardiovascular, respiratory, gastrointestinal, renal, cutaneous and neurological systems

Bettelheim P, Muhm M, Valent P, Geissler K, Andreeff M , Haimi J, Sillaber C, Hinterberger W, Vieder L, Schulz G, et al