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The results showed that 11 patients experienced mild nausea (n=6) and vomiting (n=5), with no serious adverse reactions or deaths

15 Thus, a competition for selenium incorporation would be responsible for the decrease of the biosynthesis or activity of GPxs 1 and 3 leading to accumulation of H 2 O 2 that has been suggested to exert neurotoxic effects promoting oxidative stress and inflammation, which are critical factors of brain damage induced by cerebral ischemia

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