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That makes it harder for semaglutide to do its job

For injectable semaglutide, side effects are not tied to whether youve eaten, since food doesnt affect absorption

Our findings offer comprehensive real-world evidence for the cardiovascular effectiveness of tirzepatide in clinical practice in the absence of studies with direct comparisons to semaglutide, and ahead of further evidence from the SURPASS-CVOT randomized controlled trial that compared tirzepatide against an older GLP-1 receptor agonist that is not frequently used in routine care 14,17