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doi:10.1016/j.fertnstert.2003.10.034

In the CNS, Semaglutide crosses the blood-brain barrier to act on GLP-1R-expressing neurons in the hypothalamic arcuate nucleus and other appetite-regulating centers, reducing hunger signaling and promoting satiety

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Clin Geriatr Med 40:515528 Chakaroun RM, Olsson LM, Bckhed F (2023) The potential of tailoring the gut microbiome to prevent and treat cardiometabolic disease