In vivo , Geniposide treats CIA in SD rats through intragastric administration at doses of 30, 60, and 120 mg/kg/day for 21 days, with 60 mg/kg/day identified as optimal
Dietary ascorbate is also involved in non-heme iron absorption in the small intestine and in the overall regulation of iron homeostasis
The recommendation is conditional because evidence on longterm safety, weightmaintenance, outcomes after stopping treatment, and realworld use is still limited, and because of high costs, variable healthsystem readiness and potential adverse effects on health equity (Drucker, 2022
This deficiency can also have distressing neuropsychiatric symptoms, such as depression, anxiety, dementia, and delirium