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Although we did not investigate each of these cell death pathways, we do not deny their potential roles

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4.4.4.2 Gut microbiota dysbiosis as the central driver A unifying feature across AAA, BCAA, and SAA metabolism is the pathogenic role of gut microbiota dysbiosis in DKD

Over the last decade and despite the setbacks including the recent failure of the highly promising anti-IFNR therapy, our understanding of the mechanisms of SLE contributed to expansion of the drug pipeline for SLE (Table 1)