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Discomfort during the injection is typically very mild, similar to a small pinch
When you lose fat, which patients often do on Zepbound, your hormonal levels may change, thus potentially disrupting the menstrual cycle
Article updated 12/17/2025 to reflect recent FDA communications, regulatory clarifications and clinical context related to GLP-1 medications
Semaglutide (Wegovy) for the treatment of obesity or weight management should not be used during pregnancy because weight loss offers no potential benefit to a pregnant woman and may result in fetal harm due to the potential hazard of maternal weight loss to the fetus
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