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Compounded Nasal Drug Products and the Regulatory Landscape for Unapproved Peptides Compounding pharmacies prepare customized nasal spray preparations under prescription for individual patients regulated under Section 503A of the Drug Quality and Security Act (DQSA) for traditional pharmacies, or Section 503B for outsourcing facilities

Weghuber, D., et al

Providers are increasingly seeing side effects such as: Nausea, vomiting, and delayed gastric emptying Fatigue and muscle loss during rapid weight loss Micronutrient depletion from reduced food intake Emotional dysregulation related to appetite and blood sugar swings Plateaus or weight regain after discontinuation Some patients also feel disconnected from their hunger cues or experience anxiety about long-term dependency on injections

A study by Gelander et al