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Following the KEAP1 inactivation, the expression and the nuclear translocation of nuclear factor-erythroid 2 p45-related factor 2 (NRF2) are increased, which subsequently promotes the transcription of antioxidant proteins like superoxide dismutase 2 (SOD2) and heme oxygenase 1 (HO-1), and leads to the mitigation of synovial inflammation

2020 Dec 10

(2019), the expression and function of glutamate transporters during ischemia may be dysregulated at different levels, ranging from either positive or negative transcriptional regulation, RNA splicing, epigenetic modulation, such as DNA methylation or histone modification, to post-translational glycosylation and phosphorylation

Glutamate as a marker of cognitive function in schizophrenia: a proton spectroscopic imaging study at 4 Tesla