Concurrently, FXR activation represses endothelin-1 transcription and AngII signaling to attenuate metabolic cardiac damage (Guan et al., 2022)
It has been reported that PPAR- gene expression is associated with SOD gene expression in the liver [20], and CAT has been identified as one of the target enzymes of PPAR- [34]
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142 : 8088 Marcus DL, de Leon MJ, Goldman J, Logan J, Christman DR, Wolf AP et al