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Additionally, while 3T3-L1 adipocytes have been a workhorse cell line for studying GLUT4 biology, they are immortalised mouse cells, and the field would benefit from more translational adipocyte models, such as human-derived lines or tissues

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Cofactor for L-methylmalonyl-coenzyme A mutase 5-Deoxyadenosylcobalamin is required by the enzyme that catalyzes the conversion of L-methylmalonyl-coenzyme A to succinyl-coenzyme A (succinyl-CoA), which then enters the citric acid cycle ( Figure 2 )

The effect of marizomib on the metabolism of tumor cells may be considered when developing treatment regimens for HLRCC