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The mechanism for this effect may have 2 components

Assessment of cardiovascular risk: Semaglutide has been associated with improvements in cardiovascular outcomes in patients with type 2 diabetes

Regulatory guidelines from the Medicines and Healthcare products Regulatory Agency state that only people classified as clinically obese, with a Body Mass Index (BMI) of more than 30, or those who are overweight (BMI of 27-30) with at least one weight-related health condition such as high blood pressure or type 2 diabetes, will be eligible to receive the drug

Martin Ferrillo of ASCPM (Albany Saratoga Centers for Pain Management) stresses the importance of safety, advocating for the management of such treatments exclusively under the supervision of qualified medical professionals