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In a previous study in a mouse model of Alzheimers disease, Tirzepatide did not show any protective effects and did not reduce inflammation in the brain either (61)

In light of increasing rates of both obesity and overweight in the United States, todays approval addresses an unmet medical need. The main side effects of Zepbound are gastrointestinal issues like nausea, vomiting, constipation and diarrhea, the FDA said

Studies are investigating tirzepatide specifically for NASH, with potential to address the unmet need for effective pharmacotherapy for metabolic liver disease

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