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Diameter, polydispersity, zeta potential and encapsulation efficiency of LNP-mRNA particles were determined using the NanoBrook Omni (Brookhaven), Zetaview (Particle Metrix, Germany) and Ribogreen assay (Thermo Fisher)
Specific genetic mutations that cause abnormal protein accumulation cause neurodegenerative diseases like Alzheimers and Parkinsons both of which are common types of dementias that arise from certain parts of the brain decaying faster than others
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