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Pan-cancer analyses reveal that CHAC1 expression is highly variable, being upregulated in many cancers (e.g., breast, ovarian, lung, bladder carcinomas) and downregulated in others (e.g., certain head/neck, kidney, and brain cancers) (Li, D

[DOI] [PubMed] [Google Scholar] 58.Novak P, Giannetti MP, Weller E, Hamilton MJ, Castells M

Primig M, Williams RM, Winzeler EA, Tevzadze GG, Conway AR, Hwang SY, et al

Furthermore, the relative abundance of Akkermansia , a genus positively associated with improvements in obesity-related metabolic issues 60 , was increased in the vehicle-treated group that underwent diet switch relative to the WD control group, suggesting a potential for distinct microbiome-mediated mechanisms of weight loss subsequent to diet switch from those of diet switch in combination with 5A-1MQ treatment