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But the hard cardiovascular events came in below expectations in both arms, and the MACE analyses, while pre-specified, were not sized to prove event reduction (MACE-5 hazard ratio 0.82, confidence interval crossing 1)

DeLorenzi C

Similarly, PD and AD patients had lower-than-normal hK6 content in the SN region (Ogawa et al., 2000)

The Verdict: Its No Different Than Any Other Diet When you lose a significant amount of weight by any method whether it's keto, intermittent fasting, bariatric surgery, or GLP-1syou will lose some lean mass alongside fat