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In stretch mark tissue specifically, this controlled injury disrupts the dysfunctional scar matrix and summons the cellular machinery needed to replace it

Arterioscler Thromb Vasc Biol 20:14301442 Wu M, Pritchard KA Jr, Kaminski PM, Fayngersh RP, Hintze TH, Wolin MS (1994) Involvement of nitric oxide and nitrosothiols in relaxation of pulmonary arteries to peroxynitrite

Studies have suggested that the leucine-rich repeat kinase 2 (LRRK2) protein may be specifically involved in regulating Drp1-mediated mitochondrial fission

In some instances, the link of those pathways to thiopurine responsiveness is not immediately apparent