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Obese people not only have inconvenience in life and decreased exercise capacity, but are also more susceptible to metabolic diseases, cardiovascular and cerebrovascular diseases

Medications for metabolic conditions, including diuretics and SGLT2 inhibitors, can increase urinary frequency as a side effect

Kaddurah-Daouk at Duke is PI of the Mood disorder Precision Medicine Consortium (funded by NIMH R01MH108348) and the Alzheimer Gut Microbiome Project (funded by NIA U19AG063744)

The temporal association between the onset of psychosis and the initiation of acetyl-L-carnitine suggests that the supplement may have played a role in precipitating the episode