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Moreover, variability in genetic background, diet, and environmental exposures can introduce inconsistency, while ethical concerns and cost limit the scalability of these studies (Loh & Lim, 2018a, b
The vial arrives, perfectly packaged, containing a delicate, lyophilized (freeze-dried) white powder
The BBB consists of endothelial cells tightly joined by tight junctions, supported by astrocytic end-feet and pericytes, which collectively regulate the movement of ions, nutrients, and metabolic waste across the barrier while preventing the entry of pathogens, toxins, and potentially harmful immune cells (Abbott et al., 2010)
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