Warnings and Precautions 5.1 Severe Optic Atrophy in Patients with Lebers Disease Patients with early Lebers disease (hereditary optic nerve atrophy) who were treated with vitamin B12 suffered severe and swift optic atrophy
Using Corneal Confocal Microscopy to Compare Mecobalamin Intramuscular Injections vs Oral Tablets in Treating Diabetic Peripheral Neuropathy: A RCT
A patient might misread a concentration (confusing mcg with mg), draw from the wrong vial, or inject a full reconstituted vial instead of a fractional dose
Given the high curing potential, very safe profile (lethal dose not achieved), and with a suitably wide effective range (g-ng regimens) and unlimited methods of application (i.e., intraperitoneal, intragastric, in drinking water or topically, at the site of injury) (for review, see [1,3,4,5,6,8,9,32,33,34])), it may be a real challenge for further therapy