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Following the modification the residue is hydroxylated yielding a residue in the protein termed hypusine

Clinical data highlights its role in Phase II liver detoxification, binding to toxins so they can be excreted

Without direct delivery to the bloodstream, many people cannot achieve optimal B12 levels through oral supplementation alone

Common side effects include, but may not be limited to: pain or redness at the injection site mild diarrhea pruritus (itching) increased swelling joint pain dizziness headache nervousness or anxiety Serious side effects may include: allergic reactions peripheral vascular thrombosis hypokalemia (low potassium levels) pulmonary edema (fluid build-up around or in the lungs) thrombocytosis congestive heart failure There have been reports of anaphylactic shock and death after the parenteral administration of vitamin B12