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Side effects and expert recommendations Semaglutide has been a drug on the market for years, first approved by the FDA in 2018 and by the EMA in 2019 for the treatment of type 2 diabetes mellitus

Safety was broadly consistent with known semaglutide effects, with more gastrointestinal and weight-related side effects reported

Although this large, rigorous trial can provide support for a potential new indication for semaglutide for secondary prevention of CVD, whether and how quickly payers may reimburse for such an indication is uncertain

They also inhibit a key pathway involved in the inflammatory process while activating a second pathway responsible for cell repair and energy production