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The mean triglyceride level in the GLP-1 group was 187 mg/dL with a SD of 175, and a calcium level of 9.4 mg/dL with a SD of 0.5

Therefore, for therapeutics that are targets of efflux transporters, combining device-assisted opening of the BBB with efflux transporter blockers should be considered

Key point: Week 24 vIGA-AD 0/1: 26.5% (Q4W)/29.1% (Q12W) vs 10.5%

Gastrointestinal side effects, including nausea, vomiting, diarrhoea, and constipation, are common with GLP-1 receptor agonists and may be poorly tolerated in older patients