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Melanotic neuroectodermal tumour of infancy presenting as an undifferentiated round cell tumour in the soft tissue of the forearm

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The implications of NNMT inhibition extend far beyond simple cofactor availability, influencing fundamental cellular processes including mitochondrial biogenesis, oxidative stress management, and epigenetic regulation

RM-718 and PL7737 are also selective away from MC1R and should mitigate increases in skin pigmentation