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Twenty four hours or a week after the last BrdU injection, rats were deeply anesthetized and transcardially perfused using PBS supplemented with 4 U ml 1 heparin (Merck Biosciences, Darmstadt, Germany), followed by fresh 2.5 % paraformaldehyde (J.T

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MOTS-c also shares some functional similarities with exercise mimetics and AMPK activators like metformin, though it works through distinct pathways