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In addition to age-related differences, our subgroup analyses also revealed that female people and individuals with a higher burden of comorbidities experienced greater reductions in all-cause death following GLP-1 RA therapy

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Ojima A, Ishibashi Y, Matsui T et al (2013) Glucagon-like peptide-1 receptor agonist inhibits asymmetric dimethylarginine generation in the kidney of streptozotocin-induced diabetic rats by blocking advanced glycation end product-induced protein arginine methyltranferase-1 expression