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A large 2025 study published in Blood Advances examined more than 540,000 patients with type 2 diabetes across 21 countries and found that those taking GLP-1 medications had about a 20 percent lower risk of venous blood clots compared to those taking a different class of diabetes drug

Results Interim analysis The trial was halted early in October 2023 after the DSMB performed an interim analysis after 570 events had accrued, and stopping rules were met

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