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This phenomenon may be linked to an altered ratio in anti-apoptotic and pro-apoptotic proteins

Moreover, in a prospective study, reduced glutathione administered alongside blood purification therapy significantly decreased endotoxin levels, inflammatory mediators, and hepatic injury in septic shock patients (Liu and Meng, 2024)

Similarly, the decrease in 3-methyl-2-oxovaleric acid, linked to BCAA metabolism, further supports this and indicates altered amino acid metabolism during epileptic activity 32

The side effect profile is also comparatively mild because it doesn't significantly activate the other melanocortin receptors scattered throughout the body