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In vivo antitumor efficacy assessment When the tumor volumes reached approximately 100 mm, twenty female BALB/c nude mice bearing 143B tumors were randomly assigned into four groups
Before the big trial, Athira ran a smaller Phase 2 proof-of-concept study called ACT-AD, in 77 patients
So, certain drugs like antidepressants, like Wellbutrin, bupropion, as it's commonly called, or the so-called SSRIs, the serotonin selective re- top- reuptake inhibitors, excuse me, like Prozac, Zoloft, and similar, will increase dopamine and serotonin respectively
Together we came up with a customized treatment plan
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