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In vitro and in vivo experiments confirmed that UroA is able to protect nerve cells and alleviate neurodegenerative processes such as those seen in Alzheimers disease, where autophagy and mitophagy play a significant role in the pathogenesis of such neurodegenerative diseases

For those interested in topical application methods , concentrations and formulation details matter significantly for outcomes

117 Although ACE2 is exhibited in enterocytes and pneumocytes of the alimentary canal, 118 according to studies, the alveolar type 2 cells appearance is subdued when compared to other cells that express ACE2, indicating that SARS-CoV-2 utilizes co-receptors Various safe remedies are being considered to treat COVID-19 including phage-vaccine development, use of DPP4, application of herbs etc

Therefore, future studies should prioritize delineating the tissue-specific functions of GPER, elucidating its interactions with other receptors and evaluating its therapeutic potential in various metabolic disorders