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We summarize mechanistic insights across cellular and molecular domains, critically appraise preclinical and clinical findings, and discuss translational challenges that include bioavailability and brain penetration, study heterogeneity, biomarker guided stratification, and pediatric safety

Metabolic surgery for the treatment of type 2 diabetes: a network meta-analysis of randomized controlled trials

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Melanotan II (MT-2) is a synthetic cyclic heptapeptide analogue of alpha-melanocyte stimulating hormone (-MSH)