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Expanding the therapeutic toolbox allows clinicians to tailor therapy to each individual, ensuring that every person has the most effective and well-tolerated option for long-term weight management. Liana K

The Connection Between Weight Loss and Energy Levels Many patients report feeling more energetic as pounds drop and cardiovascular fitness improves

32,33 Under physiological conditions, besides the paracrine secretion pathway in the gastrointestinal tract, most endogenous GLP-1 in circulation is locally deactivated by DPP-4 and the liver, 34 making it difficult to directly enter the CNS through the blood-brain barrier

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